Joseph K. Sheldon and David K. Foster point out that stewardship of God’s creation requires a basic knowledge of God, the owner, a personal relationship with the owner, and personal knowledge of how the creation works. In this essay they identify and discuss three environmental issues relating to the fundamental functions of the biosphere. These are areas where the Christian public—those specifically called to be stewards—typically lack sufficient knowledge to carry out their responsibility. Of particular concern are global climate change, the increasing rate of extinction, and global toxification and how these systematic perturbations change the normal functioning of the biosphere. Mr. Sheldon is Professor of Biology and Environmental Science at Messiah College, and Mr. Foster is Assistant Professor of Biology and Environmental Science at Messiah College and Director of the Oakes Museum of Natural History.