Many employee wellness programs are doomed to failure because they focus on treating the symptoms of dysfunctional organizational practices without addressing underlying causes. In particular, many fail to take seriously the necessity for a rhythm of work and rest in employees’ lives. Margaret Diddams, Lisa Surdyk, Denise Daniels, and Jeff Van Duzer examine the principles of rest, reflection, and relationships found in biblical passages pertaining to the Sabbath and review research that demonstrates their contribution to building individual well-being. They also suggest ways that organizations can develop internal cultures that work in cooperation with, rather than in opposition to, a rhythmic balance of work and rest. Ms. Diddams is Associate Professor of Psychology, Ms. Surdyk is Associate Professor of Economics, Ms. Daniels is Associate Professor of Management, and Mr. Duzer is Dean and Associate Professor of Business Law and Ethics at Seattle Pacific University.